Gastroenterologist-Lead Management of Iron Deficiency Anemia in Inflammatory Bowel Disease Is Effective, Safe, and May Increase Quality of Life

Crohns Colitis 360. 2020 Jul;2(3):otaa051. doi: 10.1093/crocol/otaa051. Epub 2020 Jun 24.

Christopher L Coe 1, Matthew H Meyers 1, Dawn B Beaulieu 1, Elizabeth Scoville 1, David A Schwartz 1, Sara N Horst 1, Robin L Dalal 1


Author information

  • 1Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA.


Background: The effectiveness and safety of gastroenterologist (GI)-lead treatment of iron deficiency anemia (IDA) in inflammatory bowel disease (IBD) have not been well-studied.

Methods: A retrospective chart review of patients with IBD, IDA, and evidence of treatment with iron at a tertiary IBD center was conducted.

Results: In 351 patients, hemoglobin and quality of life scores increased significantly after treatment with iron. Twelve of 341 patients treated with intravenous iron had an adverse effect. Twenty-seven patients required a hematology referral.

Conclusion: GIs should consider treating patients with IBD and IDA with intravenous iron as it is safe and effective.

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