Medical Management of Crohn's Disease

Cureus. 2020 May 29;12(5):e8351. doi: 10.7759/cureus.8351.

Ajay K Gade 1, Nathan T Douthit 2, Erin Townsley 3


Author information

  • 1Internal Medicine, Brookwood Baptist Medical Center, Birmingham, USA.
  • 2Medical Education Internal Medicine, Brookwood Baptist Health, Birmingham, USA.
  • 3Medical Education Internal Medicine, Brookwood Baptist Medical Center, Birmingham, USA.

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Crohn's disease (CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract from the mouth to the anus, sparing the rectum. The goal of medical therapy is to induce remission with medications, followed by the administration of maintenance medications to prevent a relapse of the disease. The concept of induction of remission and maintenance of remission is very important, as there is an overlap of medications used to induce and maintain remission. Physicians first direct treatment to induce a remission that involves relief of symptoms and mucosal healing of the lining of the colon and then provide long-term treatment to maintain the remission. Standard treatment for CD depends on the extent of involvement and disease severity, for example, mild, moderate, severe, and fulminant.

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