Abstract

Candida in IBD: Friend or Foe?

Cell Host Microbe. 2020 May 13;27(5):689-691. doi: 10.1016/j.chom.2020.04.018.

Julia Fritsch 1, Maria T Abreu 2

 
     

Author information

1Crohn's and Colitis Center, Division of Gastroenterology, Department of Medicine, University of Miami Leonard Miller School of Medicine, Miami, FL, USA.

2Crohn's and Colitis Center, Division of Gastroenterology, Department of Medicine, University of Miami Leonard Miller School of Medicine, Miami, FL, USA. Electronic address: mabreu1@med.miami.edu.

Abstract

In this issue of Cell Host & Microbe, Leonardi et al. demonstrate ulcerative colitis patients with high Candida responded best to fecal microbial transplant (FMT). However, decreased Candida post-treatment was associated with improved disease-suggesting that Candida reductions are associated with less inflammation. Pre-FMT Candida levels may identify FMT responders.

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