Abstract

ECCO Guidelines on Therapeutics in Crohn

Adamina M1,2, Bonovas S3,4, Raine T5, Spinelli A6, Warusavitarne J7, Armuzzi A8, Bachmann O9, Bager P10, Biancone L11, Bokemeyer B12, Bossuyt P13, Burisch J14, Collins P15, Doherty G16, El-Hussuna A17, Ellul P18, Fiorino G3,4, Frei-Lanter C19, Furfaro F4, Gingert C20,21, Gionchetti P22, Gisbert JP23, Gomollon F24, Lorenzo MG3, Gordon H25, Hlavaty T26, Juillerat P27, Katsanos K28, Kopylov U29, Krustins E30, Kucharzik T31, Lytras T32, Maaser C33, Magro F34, Marshall JK35, Myrelid P36, Pellino G37, Rosa I38, Sabino J39, Savarino E40, Stassen L41, Torres J42, Uzzan M43, Vavricka S44, Verstockt B45,46, Zmora O47.
J Crohns Colitis. 2019 Nov 19. pii: jjz187. doi: 10.1093/ecco-jcc/jjz187. [Epub ahead of print]

 
     

Author information

1 Department of Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland.

2 University of Basel, Basel, Switzerland.

3 Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.

4 IBD Center, Humanitas Clinical and Research Center, Milan, Italy.

5 Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.

6 Humanitas Clinical and Research Center, Division of Colon and Rectal Surgery, Humanitas University, Department of Biomedical Sciences, Milan, Italy.

7 Imperial College London, Department of Surgery and Cancer, St Mark's Hospital, Department of Gastroenterology, London, United Kingdom.

8 IBD Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS - Universita' Cattolica del Sacro Cuore, Rome, Italy.

9 Department of Internal Medicine I, Siloah St. Trudpert Hospital, Pforzheim, Germany.

10 Department of Hepatology and Gastroenterology, Aarhus University Hospital, Denmark.

11 Department of Systems Medicine, University "Tor Vergata" of Rome, Italy.

12 Gastroenterology Practice Minden, Germany.

13 Imelda GI Clinical Research Centre, Imelda General Hospital, Bonheiden, Belgium.

14 Gastrounit, medical division, Hvidovre Hospital, University of Copenhagen, Denmark.

15 Department of Gastroenterology, Royal Liverpool University Hospital, United Kingdom.

16 Department of Gastroenterology and Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland.

17 Department of Surgery, Aalborg University Hospital, Aalborg, Denmark.

18 Department of Medicine, Division of Gastroenterology, Mater Dei Hospital, Msida, Malta.

19 Departement of Surgery, Hospital Zollikerberg, Zollikerberg Zürich, Switzerland.

20 Visceral Surgery, Cantonal Hospital Winterthur, Winterthur, Switzerland.

21 Department of Human Medicine, Faculty of Health, University of Witten/Herdecke, Witten, Germany.

22 IBD Unit, DIMEC, University of Bologna, Bologna, Italy.

23 Gastroenterology Unit, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain.

24 Chief, IBD UNIT, Hospital Clíico Universitario "Lozano Blesa"; IIS Aragón, CIBEREHD, Zaragoza, Spain.

25 Department of Gastroenterology, Barts Health NHS Trust, Royal London Hospital, London, United Kingdom.

26 5th Department of Internal Medicine, Sub-department of gastroenterology and hepatology, University hospital Bratislava and Faculty of Medicine, Comenius University Bratislava, Slovakia.

27 Gastroenterology, Clinic for Visceral Surgery and Medicine, Inselspital, University Hospital of Bern, Bern, Switzerland.

28 Department of Gastroenterology and Hepatology, Division of Internal Medicine, University and Medical School of Ioannina, Ioannina, Greece.

29 Department of Gastroenterology, Tel-HaShomer Sheba Medical Center, Ramat Gan, and Sackler Medical School, Tel Aviv, Israel.

30 Department of Gastroenterology, Hepatology and Nutrition, Pauls Stradins Clinical University Hospital, Department of Internal medicine, Riga Stradinš university, Riga, Latvia.

31 Department of Internal Medicine and Gastroenterology, Hospital Lüneburg, Lüneburg, Germany.

32 National Public Health Organization, Athens, Greece.

33 Outpatients Department of Gastroenterology, Hospital Lüneburg, Lüneburg, Germany.

34 Department of Pharmacology and Therapeutics; Institute for Molecular and Cell Biology, University of Porto, Faculty of Medicine, Porto, Portugal.

35 Department of Medicine (Division of Gastroenterology) and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

36 Department of Surgery, and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

37 Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.

38 Department of Gastroenterology, IPOLFG, Lisbon, Portugal.

39 Department of Gastroenterology and Hepatology, University Hospitals, KU Leuven, Leuven, Belgium.

40 Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.

41 Department of General Surgery, Maastricht University Medical Centre+, Maastricht, The Netherlands.

42 Department of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal.

43 Department of Gastroenterology, IBD unit, Beaujon Hospital, APHP, Clichy, France.

44 Center for Gastroenterology and Hepatology, Zürich- Altstetten, Switzerland.

45 Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.

46 Department of Chronic Diseases, Metabolism and Ageing, TARGID - IBD, KU Leuven, Leuven, Belgium.

47 Department of Surgery, Shamir Medical Center (Assaf Harofe), Tel Aviv, Israel.

Abstract

This article is the second in a series of two publications relating to the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's disease. The first article covers medical management; the present article addresses surgical management, including preoperative aspects and drug management before surgery. It also provides technical advice for a variety of common clinical situations. Both articles together represent the evidence-based recommendations of the ECCO for Crohn's disease and an update of prior guidelines.

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