Levy R¹, Amarilyo G², Tal R², Amir J³, Assa A⁴, Rinawi F⁴, Harel L². J Pediatr. 2019 Mar 8. pii: S0022-3476(18)31722-0. doi: 10.1016/j.jpeds.2018.12.005. [Epub ahead of print]

Author information

1 Department of Pediatrics A, Schneider Children's Medical Center of Israel, Petach Tikva, Israel. Electronic address: Rachel.nesher@gmail.com.

2 Rheumatology Unit, Schneider Children's Medical Center of Israel, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

3 Department of Pediatrics, Mayanei Hayeshua Medical Center, Bnei Brak, Israel.

4 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Institute of Gastroenterology Hepatology and Liver Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel.

Abstract

A comparison of 23 children with inflammatory bowel disease presenting with musculoskeletal symptoms and 46 children with arthritis of other causes yielded significantly higher rates in the inflammatory bowel diseasegroup of sacroiliitis, arthralgia, additive and recurrent arthritis, microcytic anemia, elevated inflammatory markers, and hypoalbuminemia. Clinical awareness of these findings could expedite diagnosis and treatment.