AAPT Diagnostic Criteria for Chronic Abdominal, Pelvic, and Urogenital Pain: Irritable Bowel Syndrome

Zhou Q1, Wesselmann U2, Walker L3, Lee L4, Zeltzer L5, Verne GN6. J Pain. 2017 Oct 24. pii: S1526-5900(17)30737-X. doi: 10.1016/j.jpain.2017.10.002. [Epub ahead of print]
Author information

1 Department of Medicine, Tulane University School of Medicine, New Orleans, LA; Department of Veteran Affairs, Malcom Randall VAMC, Gainesville, FL. Electronic address: qzhou2@tulane.edu. 2 University of Alabama at Birmingham, Departments of Anesthesiology and Perioperative Medicine, Neurology and Psychology, Birmingham, AL. 3 Vanderbuilt University, Nashville, TN. 4 Johns Hopkins University School of Medicine, Baltimore, MD. 5 UCLA, Los Angeles, CA. 6 Department of Medicine, Tulane University School of Medicine, New Orleans, LA.


In conjuction with the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership with the US Food and Drug Administration and the American Pain Society (APS), the ACTTION-APS Pain Taxonomy (AAPT) initiative strove to develop the characteristics of a diagnostic system useful for clinical and research purposes across disciplines and types of chronic pain conditions. Following the establishment of these characteristics, a working group of clinicians and clinical and basic scientists with expertise in abdominal, pelvic, and urogenital pain began generating core diagnostic criteria and defining the related extraintestinal somatic pain and other symptoms experienced by patients. Systematic diagnostic criteria for several common abdominal, pelvic, and urogenital pain conditions are in development. Here, we present the proposed AAPT criteria for irritable bowel syndrome (IBS), the most common chronic, non-cancer abdominal pain condition. A systematic review and synthesis was conducted to complement the Rome IV Diagnostic Criteria for IBS. Future efforts will subject these proposed AAPT criteria to systematic empirical evaluation of their feasibility, reliability, and validity. The AAPT IBS criteria are part of an evidence-based classification system that provides a consistent vocabulary regarding diagnostic criteria, common features, co-morbidities, consequences, and putative mechanisms of the disorder. A similar approach is being applied to other chronic and often debilitating abdominal, pelvic, and urogenital pain conditions.

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