Lai, Mark (M);Phan, Timothy (T);Niewiadomski, Ola (O);Ding, Nik (N);

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Case Rep Gastroenterol.2025 Jun 04;19(1):392-396.doi:10.1159/000545922

Abstract

INTRODUCTION: Ulcerative colitis is a chronic inflammatory disease affecting the colon. Anti-tumor necrosis factor-alpha drugs are a cornerstone of management in ulcerative colitis both in induction and maintenance of remission. Thrombocytopenia is a rare side effect of these drugs.

CASE PRESENTATION: We present a case of infliximab-induced immune thrombocytopenic purpura in a 34-year-old female ulcerative colitis patient.

CONCLUSION: Infliximab can be a cause of drug-induced immune-related thrombocytopenia and patient's platelet counts should be regularly monitored. In patients with severe thrombocytopenia and having been recently commenced on infliximab, prompt referral to hematology specialty is essential.