Quality of life after risk reducing mastectomy in a Portuguese cohort of BRCA pathogenic/likely pathogenic variant carriers. Raposo, Maria (M);Peleteiro, Bárbara (B);Magalhães, André (A);Torres, Sandra (S);Insua-Pereira, Inês (I);Guimarães, Raquel (R);Garrido, Luzia (L);Costa, Susy (S);Fougo, José Luis (JL); |
Author information J Cancer Res Clin Oncol.2025 May 30;151(5):177.doi:10.1007/s00432-025-06231-9 Abstract PURPOSE: Women with pathogenic/likely pathogenic (P/LP) variants in BRCA1/2 genes have an increased lifetime risk of breast and ovarian cancer. Cancer risk management options include intensive breast surveillance (IBS) and risk reducing mastectomy (RRM). This study aims to compare the effect of these strategies on quality of life, anxiety, and depression to enhance shared decision-making. |
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