Abstract

Celiac disease and nonceliac enteropathies

CurrOpinGastroenterol. 2024Nov1;40(6):464469.doi:10.1097/MOG.0000000000001048. Epub 2024 Jun 14.

John B Doyle 1Benjamin Lebwohl 1 2

 
     

Author information

1Division of Digestive and Liver Diseases, Columbia University Irving Medical Center.

2The Celiac Disease Center at Columbia University, New York, New York, USA.

Abstract

Purpose of review: This review highlights recent research in the field of celiac disease.

Recent findings: Epidemiological studies continue to identify celiac disease-associated diseases such as inflammatory arthritis, irritable bowel syndrome, and cardiovascular disease. Recently published consensus guidelines provide recommendations for the long-term management and monitoring of patients with celiac disease. There are multiple pharmaceutical therapies for celiac disease under investigation, and recent phase I and phase II trials are reviewed here. Finally, a recent trial of patients with nonceliac gluten sensitivity demonstrates a significant nocebo effect in this condition.

Summary: Recent advances in celiac disease include the development of new clinical guidelines as well as promising new therapeutics. Continued high-quality research is needed to improve the outcomes of patients with celiac disease and nonceliac enteropathies.

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