J Clin Med. 2024 Sep 12;13(18):5401. doi: 10.3390/jcm13185401.

Amit Herling ¹, Tal Moshe Perluk ^2 3, Ophir Freund ^2 3, Nitsan Maharshak ^2 4, Nathaniel Aviv Cohen ^2 4

Author information

¹Faculty of Medicine, Ben-Gurion University of the Negev, Be'er Sheva 8410501, Israel.

²Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6139001, Israel.

³The Pulmonary Institute, Tel Aviv Medical Center, Tel Aviv 6423906, Israel.

⁴IBD Unit, Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center, Tel Aviv 6423906, Israel.

Abstract

This article explores the pulmonary complications associated with inflammatory bowel disease (IBD). It presents a detailed case study of a 22-year-old male with Crohn's disease exhibiting pulmonary symptoms. The review delves into the spectrum of pulmonary involvement in IBD, covering clinical presentations, diagnostic challenges, underlying pathophysiology, and management strategies. It highlights the significance of these extraintestinal manifestations on patient outcomes and quality of life. The article underscores the need for heightened clinical awareness and a systematic approach to diagnosis and management, integrating the expertise of multiple specialists. The review identifies gaps in current research, suggesting avenues for future investigation to enhance the understanding and treatment of these complex manifestations.