Diagnostics (Basel). 2023 Jun 12;13(12):2032. doi: 10.3390/diagnostics13122032.

Alexandros Toskas ¹, Faidon-Marios Laskaratos ², Sergio Coda ², Saswata Banerjee ², Owen Epstein ³

Author information

¹St Mark's Hospital, Watford Rd., Harrow HA1 3UJ, UK.

²Digestive Diseases Centre, Queen's Hospital, Barking Havering and Redbridge University Hospitals NHS Trust, Rom Valley Way, Romford RM7 0AG, UK.

³Royal Free Hospital, Pond St., London NW3 2QG, UK.

Abstract

Patients diagnosed with Crohn's disease are increasingly subjected to repeat colonoscopic and radiological examinations to assess the extent of the disease severity and the effects of treatment. Pillcam^TM Crohn's video capsule, a modified colon capsule, was developed to generate a minimally invasive mouth to rectum video of the gastrointestinal tract. The capsule provides a wide-angle panoramic mucosal view to assess inflammation, ulceration, stenosis, disease extent, and effect of treatment. This review summarizes the evidence of its utility in both adult and paediatric Crohn's disease and reviews the scoring systems used to quantify findings. The literature survey indicates that the Pillcam^TM Crohn's capsule offers high sensitivity and specificity for the detection of inflammatory lesions and the extent and distribution of disease, and it could be considered a reliable imaging modality in both adults and childhood with Crohn's disease.