Management of Sleep and Fatigue in Gastrointestinal Patients

Gastroenterol Clin North Am. 2022 Dec;51(4):829-847.doi: 10.1016/j.gtc.2022.07.007. Epub 2022 Oct 20.


Jessica K Salwen-Deremer 1Michael Sun 2


Author information

1Departments of Psychiatry and Medicine, Section of Gastroenterology & Hepatology, The Geisel School of Medicine at Dartmouth, Dartmouth-Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA. Electronic address: Jessica.k.salwen-deremer@hitchcock.org.

2Department of Psychological and Brain Sciences, Dartmouth College, 3 Maynard Street, Hanover, NH 03755, USA.


Sleep is an essential physiologic process, and unfortunately, people with gastrointestinal (GI) conditions are more likely than people in the general population to experience poor sleep quality, sleep disorders, and fatigue. Herein, we present information on common sleep disorders, fatigue, and data on these problems in various GI populations. We also discuss several treatments for sleep concerns and emerging research on the use of these treatments in GI populations. Cases that illustrate the GI/sleep relationship are presented, in addition to guidance for your own practice and cultural considerations.


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