Post-operative prevention and monitoring of Crohn's disease recurrence

Gastroenterol Rep (Oxf). 2022 Nov 16;10:goac070. doi: 10.1093/gastro/goac070.eCollection 2022.


Kate E Lee 1Sarah Cantrell 2Bo Shen 3Adam S Faye 4


Author information

1Department of Medicine, Duke University Medical Center, Durham, NC, USA.

2Duke University Medical Center Library & Archives, Duke University School of Medicine, Durham, NC, USA.

3Center for Inflammatory Bowel Diseases, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY, USA.

4Division of Gastroenterology, NYU Grossman School of Medicine, New York, NY, USA.


Crohn's disease (CD) and ulcerative colitis (UC) are relapsing and remitting chronic inflammatory diseases of the gastrointestinal tract. Although surgery for UC can provide a cure, surgery for CD is rarely curative. In the past few decades, research has identified risk factors for postsurgical CD recurrence, enabling patient risk stratification to guide monitoring and prophylactic treatment to prevent CD recurrence. A MEDLINE literature review identified articles regarding post-operative monitoring of CD recurrence after resection surgery. In this review, we discuss the evidence on risk factors for post-operative CD recurrence as well as suggestions on post-operative management.



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