Front Med (Lausanne). 2022 Oct 6;9:1025375. doi: 10.3389/fmed.2022.1025375.eCollection 2022.

Elizabeth A Spencer ¹, Manasi Agrawal ^2 3, Tine Jess ^3 4

Author information

¹Division of Pediatric Gastroenterology and Nutrition, Icahn School of Medicine, Mount Sinai Hospital, New York, NY, United States.

²Division of Gastroenterology, Icahn School of Medicine, Mount Sinai Hospital, New York, NY, United States.

³Center for Molecular Prediction of Inflammatory Bowel Disease, PREDICT, Aalborg University, Aalborg, Denmark.

⁴Department of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark.

Abstract

Personalized care in inflammatory bowel diseases (IBD) hinges on parsing the heterogeneity of IBD patients through prognostication of their disease course and therapeutic response to allow for tailor-made treatment and monitoring strategies to optimize care. Herein we review the currently available predictors of outcomes in IBD and those on the both near and far horizons. We additionally discuss the importance of worldwide collaborative efforts and tools to support clinical use of these prognostication tools.