United European Gastroenterol J. 2022 Jul;10(6):594-600. doi: 10.1002/ueg2.12265.Epub 2022 Jun 21.

Chloé Melchior ^1 2 3, Joost Algera ¹, Esther Colomier ^1 4, Hans Törnblom ¹, Magnus Simrén ^1 5

Author information

¹Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

²INSERM UMR 1073, Institute for Research and Innovation in Biomedicine, Normandy University, Rouen, France.

³Rouen University Hospital, Gastroenterology Department and INSERM CIC-CRB 1404, Rouen, France.

⁴Department of Translational Research for Gastrointestinal Disorders, University Hospital KU Leuven, University of Leuven, Leuven, Belgium.

⁵Centre for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, North Carolina, USA.

Abstract

The majority of patients with irritable bowel syndrome (IBS) experiences food-related symptoms, which are associated with high symptom burden, reduced quality of life, increased healthcare consumption and reduced intake of certain nutrients. In this review we aimed to describe a clinically useful approach for physicians, by presenting the latest progress in knowledge and its translation to management in IBS patients with food-related symptoms, as well as the underlying mechanisms involved. The research tools currently available that can be used in the future for a better characterization of this subgroup of patients are also discussed. Working towards this approach could lead to a more individualised work-up and management of IBS patients with food-related symptoms.