William J. Snape, Jr., M.D. graduated from Princeton University with a degree in chemistry. He then received his medical degree from Jefferson Medical College in Philadelphia, Pennsylvania. While at Jefferson Medical College he was elected into the scholastic honor society, Alpha Omega Alpha. He completed his postgraduate training in internal medicine at Bronx Municipal Hospital Center, Albert Einstein College of Medicine in Bronx, New York and in gastroenterology at the Hospital of the University of Pennsylvania in Philadelphia Pennsylvania. He also served for two years in the United States Navy as an internist at the Orlando Naval Hospital in Orlando, Florida.

Dr. Snape was an Assistant and Associate Professor of Medicine at the University of Pennsylvania in Philadelphia, Pennsylvania. He moved to Harbor-UCLA as Professor of Medicine and chief of the division of gastroenterology. He was funded by the National Institute of Health for research into the cause of functional gastrointestinal disease and was the Director of the Center for the Study of Inflammatory Bowel Disease funded by the National Institutes of health. He then moved to be Clinical Professor of Medicine at the University of California, Irvine.

He joined the faculty at California Pacific Medical Center to lead a cutting-edge Neurogastroenterology and Motility laboratory providing diagnostic evaluation for patients with gastrointestinal motility disorders. Dr. Snape is recognized as a foremost expert on the function of gastrointestinal smooth muscle, gastrointestinal motility studies and gastroparesis.

Neurogastroenterology
Sutter Pacific Medical Foundation

Gastroenterologists at Sutter Pacific Medical Foundation diagnose and treat a variety of digestive diseases in adults and children that may arise throughout the gastrointestinal (GI) tract. Gastroenterologists detect disorders of the stomach, intestines and related organs.For individuals with complex gastroenterology needs, our neurogastroenterology and motility physicians see individuals who have chronic abnormal muscular activity within the GI tract resulting in pain, diarrhea, constipation, vomiting or abnormal bloating. Additionally, out hepatologists are available to consult on disorders affecting the liver, such as liver cancer, hepatitis and autoimmune disorders

 Gastroparesis Registry 2 (GpR2)

To expand a registry of patients for the study of the epidemiology, etiology, and degree of morbidity associated with gastroparesis.

Estimated Enrollment: 500
Study Start Date: July 2012
Estimated Study Completion Date: September 2017
Estimated Primary Completion Date: August 2017 (Final data collection date for primary outcome measure)

 Aprepitant for the Relief of Nausea in Patients With Chronic Nausea and Vomiting of Presumed Gastric Origin Trial (APRON)

The principal objective of this multicenter, randomized, placebo-controlled trial is to evaluate whether 4 weeks of treatment with aprepitant will improve nausea as compared with placebo in patients with symptoms of chronic nausea and vomiting of presumed gastric origin.

Estimated Enrollment: 120
Study Start Date: April 2013
Estimated Study Completion Date: August 2015
Estimated Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)