Mark Pimentel, MD
Cedars-Sinai Medical Center
Los Angeles, CA

Mark Pimentel, MD, FRCPC is Director of the Gastrointestinal Motility Program and Laboratory at Cedars-Sinai Medical Center. Dr. Pimentel also serves as Associate Professor of Medicine at Cedars-Sinai Medical Center.

Board certified in internal medicine and gastroenterology, Dr. Pimentel has been awarded various investigator-driven grants related to gastrointestinal motility. His primary research interests involve irritable bowel syndrome and its relationship to small intestinal motility and bacterial overgrowth. Other interests include gastric motility in diabetes.

Dr. Pimentel is a member of several professional organizations, including the Medical Council of Canada, American Gastroenterological Association and American College of Gastroenterology. He has written articles for such peer-reviewed publications as the Annals of Internal Medicine, Archives of Internal Medicine, American Journal of Gastroenterology, Journal of Clinical Gastroenterology and Digestive Diseases and Sciences.

Dr. Pimentel received his bachelor's and medical degrees from the University of Manitoba in Winnipeg, Canada. He completed his internal medicine residency at the University of Manitoba Health Science Center. His fellowship in gastroenterology is from the UCLA Integrated Training Program in Los Angeles.

Since its founding in 1902, Cedars-Sinai has focused on providing the highest quality healthcare available. Cedars-Sinai Medical Center is composed of:

1. More than 2,000 physicians in almost every clinical specialty
2. 10,000 employees
3. 2,000 volunteers
4. 15,000 fundraising support group members

These individuals form a unique partnership in helping deliver world-class medicine to the community, and to patients from across the United States and around the world.

Cedars-Sinai physicians and scientists are leaders in basic and clinical research, bringing advancements in medicine directly from the laboratory to the bedside.

With an eye to the future, Cedars-Sinai trains the next generation of physicians, researchers and allied health professionals. More than 350 residents and fellows participate in more than 60 graduate medical education programs to learn the latest diagnostics and treatments.

Cedars-Sinai is committed to providing the highest quality patient care. Quality is measured in high patient satisfaction scores, continuous clinical performance initiatives, excellent medical outcomes, ongoing research and academic programs, and national designations and awards.

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 Double-blind, Placebo Controlled Trial Comparing Neomycin to Rifaximin Plus Neomycin in the Treatment of Methane Positive Subjects With Constipation-predominant Irritable Bowel Syndrome

In this study the investigators aim to compare the efficacy of neomycin to a combination of rifaximin and neomycin in the treatment of C-IBS subjects with methane on their breath test. This study will be conducted in collaboration with Dr. John DiBaise at the Mayo Clinic in Scottsdale, AZ.

Estimated Enrollment: 89
Study Start Date: August 2009
Estimated Study Completion Date: May 2011
Estimated Primary Completion Date: May 2011 (Final data collection date for primary outcome measure)

Ages Eligible for Study: 18 Years to 75 Years
Genders Eligible for Study: Both
Accepts Healthy Volunteers: No

 Genetics and Serum Database of Patients With Irritable Bowel Syndrome

Principal Investigator


To be able to identify individuals who are at a genetically high risk for developing IBS and to devise methods to prevent the development of this disease in such individuals

Estimated Sample Size: 500 subjects per year (IBS and Controls)

 The evaluation of intestinal methane production and weight loss after bariatric surgery

Co-Investigator

To investigate the prevalence of intestinal methane production in obese subjects who have undergone bariatric surgery

 Methane production and glycemic regulation in pre-diabetic subjects: role of methane in glycemic control

Co-Investigator

To determine the effect of enteric methane production on glucose excursions, gut transit and energy utilization in obese, prediabetic, adult subjects.

Estimated Sample Size: 15

 Pilot of AbStats /AEGIS System for Detecting Motility Abnormalities

When compared to existing analyses: manometry, Smart Pill and lactulose breath testing, external Acoustic Esophago-Gastro-Intestinal Surveillance (AEGIS) may identify unique audible patterns characteristic of features of gastroinestinal (GI) motility, gastric and small bowel contractions and emptying and small intestinal bacterial overgrowth (SIBO). This research study is designed to test the capabilities of AbStats/AEGIS to identify and associate symptoms and traditional diagnostics with sound readings and correlate this data with treatment outcomes and successes in standard of care.

Estimated Enrollment: 30
Study Start Date: July 2013
Estimated Study Completion Date: May 2015
Estimated Primary Completion Date: May 2015 (Final data collection date for primary outcome measure)

 Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial Overgrowth

The primary objective of this study is to determine whether giving SBI as a medical food starting with maintenance of health in the management of chronic loose and frequent stools in IBS-D subjects with SIBO after successful treatment with rifaximin can lead to more prolonged duration of benefit and delay symptom recurrence. SBI is the main ingredient in EnteraGamâ„¢, an orally administered prescription medical food for the dietary management of patients with enteropathy or chronic loose or frequent stools, including patients with IBS-D.

Estimated Enrollment: 60
Study Start Date: September 2014
Estimated Study Completion Date: September 2015
Estimated Primary Completion Date: September 2015 (Final data collection date for primary outcome measure)

Webcasts

Epidemiology, Burden of Illness and Diagnosis

Anthony Lembo, MD

Didactic Lecture

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Epidemiology and Burden of Illness

Scott Smilen, MD

Didactic Lecture

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Clinical Advances in the Management of Fecal Incontinence

Baharak Moshiree, MD

Didactic Lecture

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Biofeedback Therapy

Satish Rao, MD

Didactic Lecture

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Neuromodulation for the Treatment of Fecal Incontinence

Mitchell Bernstein, MD

Didactic Lecture

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Fecal Incontinence: Sphincteroplasty

Andreas Kaiser, MD

Didactic Lecture

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Fecal Incontinence: Epidemiology & Burden of Illness

Lucinda Harris, MD

Didactic Lecture

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Dietary and Lifestyle Management of Fecal Incontinence

William Chey, MD

Didactic Lecture

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A Case of Fecal Incontinence: Medical and Interventional Treatment Options

Darren Brenner, MD

Case Study

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Diagnostic Testing of Fecal Incontinence

Satish Rao, MD

Didactic Lecture

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Xpert Perspectives from DDW 2014: Reporting on Fecal Incontinence

William Chey, MD and Mark Pimentel, MD

Didactic Lecture

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eMonograph

Developing a Clinical Research Agenda for Fecal Incontinence

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Fecal Incontinence: Scope, Impact, Diagnosis, and Management

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Webcasts

Epidemiology, Burden of Illness and Diagnosis

Anthony Lembo, MD

Didactic Lecture

view details >

Epidemiology and Burden of Illness

Scott Smilen, MD

Didactic Lecture

view details >

Clinical Advances in the Management of Fecal Incontinence

Baharak Moshiree, MD

Didactic Lecture

view details >

Biofeedback Therapy

Satish Rao, MD

Didactic Lecture

view details >

Neuromodulation for the Treatment of Fecal Incontinence

Mitchell Bernstein, MD

Didactic Lecture

view details >

Fecal Incontinence: Sphincteroplasty

Andreas Kaiser, MD

Didactic Lecture

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Fecal Incontinence: Epidemiology & Burden of Illness

Lucinda Harris, MD

Didactic Lecture

view details >

Dietary and Lifestyle Management of Fecal Incontinence

William Chey, MD

Didactic Lecture

view details >

A Case of Fecal Incontinence: Medical and Interventional Treatment Options

Darren Brenner, MD

Case Study

view details >

Diagnostic Testing of Fecal Incontinence

Satish Rao, MD

Didactic Lecture

view details >

Xpert Perspectives from DDW 2014: Reporting on Fecal Incontinence

William Chey, MD and Mark Pimentel, MD

Didactic Lecture

view details >

Dinner Meetings

Clinical Advances in the Management of Fecal Incontinence
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Audiocasts

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Webcasts

An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

Didactic Lecture

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Beyond Gut Instincts: Applying the latest IBS advances to practice

William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

Didactic Lecture

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Functional dyspepsia: A new disease model

Nick Talley, MD

Didactic Lecture

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Integrating Novel Diagnostic Strategies into Practice: Key Points

Stanley Cohen, MD

Didactic Lecture

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Novel Strategies for IBS-C

Mark Pimentel, MD

Didactic Lecture

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Diagnosis and Treatment of SIBO

Satish Rao, MD

Didactic Lecture

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Insights into Lactose Intolerance

Yuri Saito, MD

Didactic Lecture

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Chronic Nausea and Vomiting: It's not always gastroparesis

Lawrence Schiller, MD

Didactic Lecture

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Management of Severe Constipation: Dysnnergic Defecation and OIC

Philip Schoenfeld, MD

Didactic Lecture

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Rifaximin for IBS-D

Philip Schoenfeld, MD

Didactic Lecture

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Diagnostic Testing in Irritable Bowel Syndrome

Brennan Spiegel, MD

Didactic Lecture

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Which Diet is Right for IBS?

William Chey, MD

Didactic Lecture

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Emerging Medical Management Options for IBS-D

William Chey, MD

Didactic Lecture

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Opioid Induced Constipation

Brooks Cash, MD

Didactic Lecture

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Overview of IBS-C Therapies

Christine Frissora, MD

Didactic Lecture

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A Primer on the Diagnosis and Management of Functional Dyspepsia

Brian Lacy, MD

Didactic Lecture

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Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

Lucinda Harris, MD

Didactic Lecture

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New IBS Biomarker

Mark Pimentel, MD

Didactic Lecture

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Understanding and Managing Gastroparesis

Linda Nguyen, MD

Didactic Lecture

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Opioid-Induced Bowel Dysfunction

Darren Brenner, MD

Didactic Lecture

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Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

Didactic Lecture

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Xpert Perspectives: Reporting on FGIMDs

Lin Chang, MD, William Chey, MD, Mark Pimentel, MD,

Didactic Lecture

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Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

Didactic Lecture

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eMonograph

An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

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Advances in IBS

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IBS News Tonight

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Advances in the Management of FGIDs

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Gastroparesis: Diagnosis and Management

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Managing the Gastrointestinal Effects of Opioids

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Painful Diverticular Disease or Irritable Bowel Syndrome?

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Advances in IBS 2012

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Implementing Effective Patient Communication Skills in IBS

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Dietary Interventions in IBS: An Update

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New and Emerging Pharmacologic Therapies for Irritable Bowel Syndrome with Diarrhea

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Advances in the Management of Irritable Bowel Syndrome: A Report from Digestive Disease Week 2011

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The Gut Microbiome and Irritable Bowel Syndrome: Is There a Link?

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Webcasts

An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

Didactic Lecture

view details >

Beyond Gut Instincts: Applying the latest IBS advances to practice

William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

Didactic Lecture

view details >

Functional dyspepsia: A new disease model

Nick Talley, MD

Didactic Lecture

view details >

Integrating Novel Diagnostic Strategies into Practice: Key Points

Stanley Cohen, MD

Didactic Lecture

view details >

Novel Strategies for IBS-C

Mark Pimentel, MD

Didactic Lecture

view details >

Diagnosis and Treatment of SIBO

Satish Rao, MD

Didactic Lecture

view details >

Insights into Lactose Intolerance

Yuri Saito, MD

Didactic Lecture

view details >

Chronic Nausea and Vomiting: It's not always gastroparesis

Lawrence Schiller, MD

Didactic Lecture

view details >

Management of Severe Constipation: Dysnnergic Defecation and OIC

Philip Schoenfeld, MD

Didactic Lecture

view details >

Rifaximin for IBS-D

Philip Schoenfeld, MD

Didactic Lecture

view details >

Diagnostic Testing in Irritable Bowel Syndrome

Brennan Spiegel, MD

Didactic Lecture

view details >

Which Diet is Right for IBS?

William Chey, MD

Didactic Lecture

view details >

Emerging Medical Management Options for IBS-D

William Chey, MD

Didactic Lecture

view details >

Opioid Induced Constipation

Brooks Cash, MD

Didactic Lecture

view details >

Overview of IBS-C Therapies

Christine Frissora, MD

Didactic Lecture

view details >

A Primer on the Diagnosis and Management of Functional Dyspepsia

Brian Lacy, MD

Didactic Lecture

view details >

Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

Lucinda Harris, MD

Didactic Lecture

view details >

New IBS Biomarker

Mark Pimentel, MD

Didactic Lecture

view details >

Understanding and Managing Gastroparesis

Linda Nguyen, MD

Didactic Lecture

view details >

Opioid-Induced Bowel Dysfunction

Darren Brenner, MD

Didactic Lecture

view details >

Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

Didactic Lecture

view details >

Xpert Perspectives: Reporting on FGIMDs

Lin Chang, MD, William Chey, MD, Mark Pimentel, MD,

Didactic Lecture

view details >

Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

Didactic Lecture

view details >

Dinner Meetings

Content available soon

Audiocasts

Content available soon!

Content available soon!

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