David Kunkel, MD
UC San Diego Health
San Diego, CA

David C. Kunkel, MD is an Assistant Clinical Professor of Medicine at the University of California, San Diego, where he also serves as the Associate Director of the GI Motility and Physiology Program. Dr. Kunkel’s area of research and specialized training is in GI motility and functional disorders. Dr. Kunkel received an American Neurogastroenterology and Motility Society (ANMS) clinical award, which he used to obtain specialized training in defecatory disorders and anorectal biofeedback therapy. He has developed the university’s anorectal biofeedback program to treat patients with pelvic floor disorders including fecal incontinence and outlet constipation. Dr. Kunkel’s research interests include irritable bowel syndrome, gastroparesis, biofeedback therapy, and breath testing. His research has been published in a variety of peer-reviewed journals, including The American Journal of Gastroenterology, Gastrointestinal Endoscopy, and Neurogastroenterology & Motility. He has published several high impact studies in the field of GI motility and functional disorders, including on post-infectious IBS, methane production in constipation, and use of a GLP-1 agonist for treatment of short bowel syndrome. Dr. Kunkel obtained his Bachelor of Science in biology from the University of New Mexico in Albuquerque. After a year of study at the National Institutes of Health under an intramural research training award, he returned to the University of New Mexico and earned his medical degree in 2008. Dr. Kunkel completed his residency in internal medicine at Cedars-Sinai Medical Center. His fellowship in gastroenterology is from the University of California, Los Angeles (UCLA) integrated training program in digestive diseases.

The UC San Diego Division of Gastroenterology treats patients with a wide range of gastrointestinal diseases, including: • Gastrointestinal motility disorders • Functional disorders including irritable bowel syndrome • Esophageal disorders • Liver disease • Colon cancer and polyposis syndromes • Pancreatic disease • Hepatitis • Biliary diseases • Inflammatory bowel disease • Peptic ulcer disease • Celiac sprue UC San Diego’s specialists, who are nationally and internationally recognized, have particular clinical expertise in liver transplantation, advanced endoscopic procedures, GI motility, functional disorders, celiac disease, and molecular diagnostics of gastrointestinal cancer. We are also leaders in the fields of minimally-invasive and robotic surgical techniques designed to help our patients recover more quickly and with less scarring. The division’s faculty members are engaged in clinical, basic science, and translational research to further advance the understanding and treatment of gastrointestinal disease. We look forward to working with our patients in the successful management of all GI conditions, from esophageal disorders and inflammatory bowel disease to pancreatic-biliary disorders and gastrointestinal cancers. To schedule an appointment, please call the Gastroenterology clinic at 619-543-2347.

 12. Pace LA, Kunkel DC, Crowe SE. Managing Celiac Disease: A Brief Overview. The New Gastroenterologist. 2016 Winter Issue:12-19. Cover article: http://www.gihepnews.com/view-pdf.html?file=fileadmin/content_pdf/gihep/2016/NEWGI_Winter16_LowRes

 11. Huang B, Kunkel D, El Kabany M. Acute Liver Failure Following One Year of Daily Consumption of a Sugar-Free Energy Drink. ACG Case Rep J 2014;1(4):214–216. http://dx.doi.org/10.14309/crj.2014.57. eCollection 2014 Jul. PMID: 26157880.

 10. Jamil LH, Huang BL, Kunkel D, Jayaraman V, Soffer EE. Successful gastric volvulus reduction and gastropexy using a dual endoscope technique. Case Rep Med. 2014;2014:136381. Epub 2014 Jan 19. PMID: 24563653.

 9. Huang BL, Kunkel D, So LY, Conklin JL. Using a stent extractor for a case of pill impaction: a novel approach. Gastrointest Endosc. 2014 Jan;79(1):185-6. PMID: 24342600.

 8. Ocampo LH, Kunkel DC, Yen A, Tan CR, Leung JW, Leung FW. Underwater hot and cold snare polypectomy can be safely executed during water exchange colonoscopy. J Interv Gastroenterol. 2013 Jul;3(3):104-106. PMID: 24478929.

 7. Tan C, Kunkel D, Ocampo LH, Sanmiguel CP, Karsan S, Cohen H, Leung FW. A novel application of the water exchange method in the treatment of sigmoid volvulus: a report of two cases. J Interv Gastroenterol. 2013 Jan;3(1):28-30. PMID: 24147224.

 6. Kunkel D, Basseri B, Low K, Lezcano S, Soffer EE, Conklin JL, Mathur R, Pimentel M. Efficacy of the glucagon-like peptide-1 agonist exenatide in the treatment of short bowel syndrome. Neurogastroenterol Motil. 2011 Aug;23(8):739-e328. PMID: 21557790.

 5. Morales W, Pimentel M, Hwang L, Kunkel D, Pokkunuri V, Basseri B, Low K, Wang H, Conklin JL, Chang C. Acute and Chronic Histological Changes of the Small Bowel Secondary to C. jejuni Infection in a Rat Model for Post-Infectious IBS. Dig Dis Sci. 2011 Sep;56(9):2575-84. PMID: 21409374.

 4. Basseri RJ, Kunkel D, Low K, Conklin JL, Pimentel M. Importance of Diarrhea in Evaluating Constipation in Irritable Bowel Syndrome Clinical Studies. J Clin Gastroenterol. 2011 Oct;45(9):790-3. PMID: 21301356.

 3. Kunkel D, Basseri RJ, Makhani MD, Chong K, Chang C, Pimentel M. Methane on Breath Testing Is Associated with Constipation: A Systematic Review and Meta-analysis. Dig Dis Sci. 2011 Jun;56(6):1612-8. Epub 2011 Feb 1. PMID: 21286935.

 2. Gebert C, Kunkel D, Grinberg A, Pfeifer K. H19 imprinting control region methylation requires an imprinted environment only in the male germ line. Mol Cell Biol. 2010 Mar;30(5):1108-15. Epub 2009 Dec 28. PMID: 20038532.

 1. El-Serag HB, Sonnenberg A, Jamal MM, Kunkel D, Crooks L, Feddersen RM. Characteristics of intestinal metaplasia in the gastric cardia. Am J Gastroenterol. 1999 Mar;94(3):622-7. PMID: 10086641.

 The UC San Diego GI Motility and Physiology specialists are involved in numerous research studies to improve the detection and treatment of motility and functional disorders. Our research is focused on these areas: • Botox injection for outlet constipation • Esophageal motility and pain • Gastroparesis electromyography patterns to better understand the changes in the electrical pacemaker cells of the stomach • Pelvic floor disorders as they relate to fecal incontinence and constipation • Innovative approaches to anorectal biofeedback therapy • Research using non-invasive three-dimensional ultrasound imaging of the anorectum

    Webcasts

    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

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    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    eMonograph

    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    view details >

    Advances in IBS

    view details >

    IBS News Tonight

    view details >

    Gastroparesis: Diagnosis and Management

    view details >

    Managing the Gastrointestinal Effects of Opioids

    view details >

    Webcasts

    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

    view details >

    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

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