Brennan Spiegel, MD
Cedars Sinai
Los Angeles, CA

After earning his bachelor's degree in Philosophy from Tufts University, Dr. Spiegel obtained his medical degree from New York Medical College. He completed his residency at Cedars-Sinai's Department of Medicine and was a fellow of the UCLA Training Program in Digestive Diseases. He completed his master's degree in Health Services at UCLA, and he teaches cost-effectiveness analysis and health analytics in the UCLA Fielding School of Public Health. Clinically, Dr. Spiegel has expertise in gastroenterology, with a focus on irritable bowel syndrome, acid reflux disease, dyspepsia, and functional gastrointestinal disorders.

In addition to authoring best selling medical textbooks, Dr. Spiegel has published numerous book chapters, abstracts, editorials and more than 130 articles in peer-reviewed journals. He serves on the Advisory Board of Editors for Clinical Gastroenterology and Hepatology and the Editorial Board for Alimentary Pharmacology & Therapeutics, and he is associate editor for the American Journal of Gastroenterology. A prolific speaker, Dr. Spiegel has been invited to present on his areas of expertise at the national and international levels.

Dr. Spiegel is a member of several professional organizations and is a fellow of the American College of Gastroenterology, the American Gastroenterological Association and the Rome Foundation.

Cedars-Sinai is known for providing the highest quality patient care. Our dedication to excellence, compassion and innovation is rooted in the Judaic tradition and its devotion to the art and science of healing, which informs every aspect of our four-fold mission:

- Leadership and excellence in delivering quality healthcare services
- Expanding the horizons of medical knowledge through biomedical research
- Educating and training physicians and other healthcare professionals
- Striving to improve the health status of our community

We live this mission every day through the contributions of more than 2,000 physicians in every clinical specialty, 10,000 employees, 2,000 volunteers and 15,000 fundraising support group members. Together we provide world-class medicine to our patients, our community, and patients from across the United States and around the world.

Physicians and scientists at Cedars-Sinai are engaged in basic and clinical research to bring medical advancements directly from the laboratory to the bedside. As the largest academic medical center in the western United States, we’re also training the next generation of physicians, researchers and allied health professionals, with more than 350 residents and fellows participating in over 60 graduate medical education programs.

 Construct validity of the Patient Reported Outcomes Measurement Information System (PROMIS®) gastrointestinal symptom scales in systemic sclerosis.

 GERD Symptoms in the General Population: Prevalence and Severity Versus Care-Seeking Patients.

 Effect of Antidepressants and Psychological Therapies, Including Hypnotherapy, in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis.

 Development and validation of a disease-targeted quality of life instrument for chronic diverticular disease: the DV-QOL.

 Reducing VA No-Shows: Evaluation of Predictive Overbooking Applied to Colonoscopy (No-show)

In this research study, investigators use colonoscopy as a case example to evaluate a predictive overbooking model derived using patient-level predictors of absenteeism. The no-show overbooking intervention employs a logistic regression model that uses patient data to predict the odds of no-showing with 80% accuracy. These projected no-show appointments will be overbooked by clerks for patients who agree to join a "fast track" short-call line. By rapidly processing endoscopy patients and moving them out of traditional slots, investigators predict more scheduling slots would become available for patients awaiting colonoscopy.

Estimated Enrollment: 500
Study Start Date: July 2013
Estimated Study Completion Date: October 2015
Estimated Primary Completion Date: October 2014 (Final data collection date for primary outcome measure)

 Predictive Validity of Acoustic Gastrointestinal Surveillance (AGIS) in Post-Operative Feeding

This study will measure the accuracy of a disposable, non-invasive device for the continuous monitoring of abdominal sounds, called the AGIS sensor (Acoustic Gastro-Intestinal Surveillance) in predicting patients' intolerance to feeding (defined as severe nausea, vomiting, or need to place a nasogastric tube within 4 hours of initiating a standard feeding protocol) following abdominal surgery. This will be a multi-site, pragmatic, observational study.

Estimated Enrollment: 300
Study Start Date: December 2013
Estimated Study Completion Date: November 2014
Estimated Primary Completion Date: November 2014 (Final data collection date for primary outcome measure)

    Webcasts

    Xpert Perspectives on OIC from DDW 2017 in Chicago, IL

    William D. Chey, MD

    Didactic Lecture

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    Negative Effects of Opioids on the Gastrointestinal Tract and The Development of Newer Therapeutics To Overcome Them

    Darren M. Brenner, MD

    Didactic Lecture

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    Optimizing Management of IBS-C and CIC

    Nicholas J. Talley, MD (chair), Darren M. Brenner, MD, William D. Chey, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

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    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

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    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    eMonograph

    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    view details >

    Advances in IBS

    view details >

    IBS News Tonight

    view details >

    Gastroparesis: Diagnosis and Management

    view details >

    Managing the Gastrointestinal Effects of Opioids

    view details >

    Webcasts

    Xpert Perspectives on OIC from DDW 2017 in Chicago, IL

    William D. Chey, MD

    Didactic Lecture

    view details >

    Negative Effects of Opioids on the Gastrointestinal Tract and The Development of Newer Therapeutics To Overcome Them

    Darren M. Brenner, MD

    Didactic Lecture

    view details >

    Optimizing Management of IBS-C and CIC

    Nicholas J. Talley, MD (chair), Darren M. Brenner, MD, William D. Chey, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

    view details >

    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    Brian E. Lacy, MD (chair), Darren M. Brenner, MD, Brooks D. Cash, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Dinner Meetings

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