Brooks Cash, MD
University of Texas Health Science Center at Houston
Houston, TX

Chief, Division of Gastroenterology, Hepatology, and Nutrition University of Texas Health Science Center at Houston Co-director, Ertan Digestive Diseases Center Visiting Professor of Medicine University of Texas McGovern Medical School Houston, TX

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 Barrett's Esophagus Study (BEST) Trial - a Multi-Center and Endoscopic Outcomes Project

This trial is a multi-center clinical and endoscopic outcomes project involving a single large database of patients with Barrett's Esophagus (BE). The initial goal of this project is to define the incidence and prevalence of cancer and high-grade dysplasia (HGD) in patients with BE. Thus, our hypothesis is that systematic collection of data on the natural history of BE and risk factors for progression of BE will provide useful information to develop a decision model for risk stratification and risk reduction strategies in BE.

Estimated Enrollment: 2500
Study Start Date: November 2007
Estimated Study Completion Date: November 2017
Estimated Primary Completion Date: November 2017 (Final data collection date for primary outcome measure)

Ages Eligible for Study: 18 Years to 80 Years
Genders Eligible for Study: Both
Accepts Healthy Volunteers: Yes
Testing Method: Probability Sample



 High Resolution Optical Imaging of the Esophagus Using the NvisionVLE™ Imaging System Registry

This is a prospective, multi-site registry with longitudinal follow up for patients undergoing EGD or endoscopy. The primary objective is to provide a collection of patient NvisionVLE™ procedural data for participating physicians, including, but not limited to, imaging data, clinical utility data, demographics, pathology, treatment, and surveillance.

Up to 1000 patients from up to 20 sites nationwide.

There are no protocol defined follow up visits. Patients will undergo an initial baseline Volumetric Laser Endomicroscopy (VLE) procedure. A patient with a negative screening examination may not require additional screening endoscopies. For patients with established disease, further surveillance endoscopies will vary based on the extent of the disease (e.g. every 3 months, every 6 months, annual), which is based on the following American Society for Gastrointestinal Endoscopy (ASGE) guideline: the role of endoscopy in the surveillance of premalignant conditions of the upper GI tract. If patients have additional VLE procedures during the enrollment period, associated data will be collected.

Estimated Enrollment: 1000
Study Start Date: July 2014
Estimated Primary Completion Date: November 2015 (Final data collection date for primary outcome measure)

Genders Eligible for Study: Both
Accepts Healthy Volunteers: No
Sampling Method: Non-Probability Sample

    Webcasts

    Holistic Approach to Diagnosis and Management of Irritable Bowel Syndrome

    Amy Kassebaum, PA-C

    Didactic Lecture

    view details >

    Opioid Induced and Exacerbated Constipation Importance, Definitions and Rationale for a Change in Nomenclature

    Amy Kassebaum, PA-C

    Didactic Lecture

    view details >

    Small Intestinal Bacterial (SIBO) and Fungal Overgrowth (SIFO)

    Nicole Martinez de Andino, RD, APRN

    Didactic Lecture

    view details >

    Behavioral Medicine for Digestive Health

    Sarah Quinton, PsyD

    Didactic Lecture

    view details >

    Trial By Jury

    Brooks Cash, MD; William D. Chey, MD; Anthony Lembo, MD; Baha Moshiree, MD; Mark Pimentel, MD

    Didactic Lecture

    view details >

    IBS Prime

    Brooks Cash, MD; Philip Schoenfeld, MD;

    Didactic Lecture

    view details >

    Xpert Perspectives on IBS from ACG/WCOG in Orlando

    William D. Chey, MD; Brian E. Lacy, MD; Mark Pimentel, MD

    Didactic Lecture

    view details >

    Xpert Perspectives on OIC from DDW 2017 in Chicago, IL

    William D. Chey, MD

    Didactic Lecture

    view details >

    Negative Effects of Opioids on the Gastrointestinal Tract and The Development of Newer Therapeutics To Overcome Them

    Darren M. Brenner, MD

    Didactic Lecture

    view details >

    Optimizing Management of IBS-C and CIC

    Nicholas J. Talley, MD (chair), Darren M. Brenner, MD, William D. Chey, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    eMonograph

    An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice

    view details >

    Advances in IBS

    view details >

    IBS News Tonight

    view details >

    Gastroparesis: Diagnosis and Management

    view details >

    Managing the Gastrointestinal Effects of Opioids

    view details >

    Implementing Effective Patient Communication Skills in IBS

    view details >

    Webcasts

    Holistic Approach to Diagnosis and Management of Irritable Bowel Syndrome

    Amy Kassebaum, PA-C

    Didactic Lecture

    view details >

    Opioid Induced and Exacerbated Constipation Importance, Definitions and Rationale for a Change in Nomenclature

    Amy Kassebaum, PA-C

    Didactic Lecture

    view details >

    Small Intestinal Bacterial (SIBO) and Fungal Overgrowth (SIFO)

    Nicole Martinez de Andino, RD, APRN

    Didactic Lecture

    view details >

    Behavioral Medicine for Digestive Health

    Sarah Quinton, PsyD

    Didactic Lecture

    view details >

    Trial By Jury

    Brooks Cash, MD; William D. Chey, MD; Anthony Lembo, MD; Baha Moshiree, MD; Mark Pimentel, MD

    Didactic Lecture

    view details >

    IBS Prime

    Brooks Cash, MD; Philip Schoenfeld, MD;

    Didactic Lecture

    view details >

    Xpert Perspectives on IBS from ACG/WCOG in Orlando

    William D. Chey, MD; Brian E. Lacy, MD; Mark Pimentel, MD

    Didactic Lecture

    view details >

    Xpert Perspectives on OIC from DDW 2017 in Chicago, IL

    William D. Chey, MD

    Didactic Lecture

    view details >

    Negative Effects of Opioids on the Gastrointestinal Tract and The Development of Newer Therapeutics To Overcome Them

    Darren M. Brenner, MD

    Didactic Lecture

    view details >

    Optimizing Management of IBS-C and CIC

    Nicholas J. Talley, MD (chair), Darren M. Brenner, MD, William D. Chey, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Improving Patient Outcomes in IBS-D: New Evidence on Epidemiology, Pharmacology, and Mgmt

    Lin Chang, MD (chair), William D. Chey, MD, FACG, AGAF, FACP, RFF, Mark Pimentel, MD, FRCP(C), Philip S. Schoenfeld, MD, MSEd, MSc (Epi)

    Didactic Lecture

    view details >

    Beyond Gut Instincts: Applying the latest IBS advances to practice

    William D. Chey, MD, Stanley A Cohen, MD, Nicholas Talley, MD, Mark Pimentel, MD, Philip S. Schoenfeld, MD

    Didactic Lecture

    view details >

    Functional dyspepsia: A new disease model

    Nick Talley, MD

    Didactic Lecture

    view details >

    Integrating Novel Diagnostic Strategies into Practice: Key Points

    Stanley Cohen, MD

    Didactic Lecture

    view details >

    Novel Strategies for IBS-C

    Mark Pimentel, MD

    Didactic Lecture

    view details >

    Management of Severe Constipation: Dysnnergic Defecation and OIC

    Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Which Diet is Right for IBS?

    William Chey, MD

    Didactic Lecture

    view details >

    Emerging Medical Management Options for IBS-D

    William Chey, MD

    Didactic Lecture

    view details >

    Overview of IBS-C Therapies

    Christine Frissora, MD

    Didactic Lecture

    view details >

    A Primer on the Diagnosis and Management of Functional Dyspepsia

    Brian Lacy, MD

    Didactic Lecture

    view details >

    Distinguishing Celiac Disease, Non-Gluten Sensitivity and IBS

    Lucinda Harris, MD

    Didactic Lecture

    view details >

    Understanding and Managing Gastroparesis

    Linda Nguyen, MD

    Didactic Lecture

    view details >

    Opioid-Induced Bowel Dysfunction

    Darren Brenner, MD

    Didactic Lecture

    view details >

    Xpert Perspectives: New Insights into the Recognition and Management of FGIMDs 2015

    Brooks Cash, MD, William Chey, MD, Mark Pimentel, MD

    Didactic Lecture

    view details >

    Gi News Tonight: Case Discussions on Functional GI and Motility Disorders

    Lawrence Schiller, MD, Lin Chang, MD, Mark Pimentel, MD, Philip Schoenfeld, MD

    Didactic Lecture

    view details >

    Dinner Meetings

    Content available soon

    Audiocasts

    Content available soon!

    Content available soon!

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